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#cancer

29 posts29 participants0 posts today
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JL Lycette MD, author🩺📚

I can’t get over the cognitive dissonance of spending 12 hours of intense work in clinic, using every minute of my 25 years of training and experience to formulate treatment plans for my patients with #cancer, and then to come home and check the news and to read about every part of the infrastructure needed to attain the knowledge for these treatment plans bring intentionally dismantled

#MedMastodon#healthcare#science
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Hippy Steve

They're getting really close to having individually customized mRNA #cancer vaccines. You get cancer, they scan it for unique protein markers & produce a custom vaccine that trains your own immune system to fight it.

Thanks to the far right's demonization of vaccines and especially mRNA ones, this is likely to eventually undo all their efforts at fighting The 'Great Replacement' conspiracy theory that lies behind their abortion and immigration policies. Will probably reduce the number of unhinged lefties too. Hurray for evolution.

h/t @ned

here's a paywall busted version of his Wired link: archive.is/cfmRM

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Ned Yeung

The mRNA technology behind coronavirus vaccines is now being used to create bespoke vaccines for cancer patients.

"Cancer vaccines weren’t a proper field of research before the pandemic. There was nothing. Apart from one exception, pretty much every clinical trial had failed. With the pandemic, however, we proved that mRNA vaccines were possible.

mRNA cancer vaccines work by giving the body instructions to make a harmless piece of a cancer-related protein. This trains the immune system to recognize and attack cancer cells carrying that protein. Think of it like a training manual for security guards. The vaccine gives the immune system a guide on what cancer looks like, so it knows exactly who to watch for and remove.

Going from mRNA Covid vaccines to mRNA cancer vaccines is straightforward: same fridges, same protocol, same drug, just a different patient.

In the current trials, we do a biopsy of the patient, sequence the tissue, send it to the pharmaceutical company, and they design a personalized vaccine that’s bespoke to that patient’s cancer. That vaccine is not suitable for anyone else. It’s like science fiction.

The UK was ready. We had fridges and we had world-class manufacturing and research facilities. During the pandemic, we had proven we could open and deliver clinical trials fast. Also, the UK had established a genomic global lead with Genomics England and the 100,000 Genome Project. All doctors and nurses in this country are trained in genomics.

So the UK government signed two partnerships: one with BioNTech to provide 10,000 patients with access to personalized cancer treatments by 2030, and a 10-year investment with Moderna in an innovation and technology center with capacity to produce up to 250 million vaccines. The stars were aligned.

For many years, we believed that research is inherently slow. It used to take 20 years to get a drug to market. Most cancer patients, unfortunately, will succumb by the time a drug gets to market. We showed the world that it could be done in a year if you modernize your process, run parts of the process in parallel, and use digital tools.

We have a trial to stop skin cancer coming back after you cut it out. It’s now completed. We over-recruited again, just like every single one of the trials that we ran, and the trial finished one year ahead of schedule. That’s completely unheard of in cancer trials because they normally run over-long.

What will happen now is that, over the next six to 12 months, we will monitor the people in the trial and work out if there’s a difference between the people who took the cancer vaccine and the ones who didn’t. We’re hoping to have results by the end of the year or beginning of 2026. If it’s successful, we will have invented the first approved personalized mRNA vaccine, within only five years of the first licensed mRNA vaccine for Covid. That’s pretty impressive."

- Dr. Lennard Lee, UK National Health Service oncologist and medical director at the Ellison Institute of Technology in Oxford

wired.com/story/wired-health-l

WIRED · Covid Vaccines Have Paved the Way for Cancer VaccinesBy João Medeiros
#cancer#vaccination#Science
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Bytes Europe

Democratic Rep. Raúl M. Grijalva of Arizona dies at 77 byteseu.com/827807/ #AdelitaGrijalva #America #Arizona #ArizonaStateGovernment #AZStateWire #BarackObama #BernieSanders #Cancer #DavidSchweikert #DistrictOfColumbia #GeneralNews #GovernmentAndPolitics #HakeemJeffries #NotableDeaths #Politics #RalM.Grijalva #ReginaRomero #RubenGallego #SylvesterTurner #Tucson #UnitedStates #UnitedStatesHouseOfRepresentatives #UnitedStatesOfAmerica #US #USNews #USA #USANews #WashingtonNews

Bytes Europe · Democratic Rep. Raúl M. Grijalva of Arizona dies at 77WASHINGTON (AP) — Democratic Rep. Raúl M. Grijalva, a champion of environmental protections and progressive ideals who took on principled but often futile causes during a two-decade career in Congress, died Thursday.Grijalva, who was 77, had risen to chair the U.S. House Natural Resources Committee during his 12 terms representing southern Arizona, a powerful perch he used to shape the nation’s environmental policies. He was known for reliably going to bat for immigrants and Native American tribes, and for the bolo tie he wore at home in Tucson and in the Capitol in Washington.Grijalva died of complications from cancer treatment,
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Black White Blue in the South

In our most captivating episode to date, we spoke with Phillip and Caroline Dennis, two ordained pastors who were in the air nearly 25 years ago while the attacks of 9/11 were happening. Their plane was diverted to a small town in Canada along with dozens of others, a heartwarming tale of humanity and compassion that was captured in the award-winning musical, Come From Away.

1/2

#SouthCarolina#SCPol#SCPolitics
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Marie 🇸🇪

Scientists at KAIST have made a groundbreaking discovery in cancer treatment by reversing colon cancer cells back into normal ones instead of destroying them. This approach focuses on using digital twin technology to simulate & analyze gene interactions, identifying key molecular switches that trigger this transformation.

If further research supports these findings, it could revolutionize cancer therapy, providing new hope for patients worldwide.

Bye cancer! South Korean scientists unveil technology that turns cancer cells back into normal cells. Credits): KAIST/Keck School of Medicine.
#cancer#southkorea#Science
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Steve Thompson PhD

Evil brother to Propaganda is Censorship.

"National Cancer Institute Employees Can’t Publish Information on These Topics Without Special Approval"

propublica.org/article/nationa

Vaccines. Fluoride. Autism. Communications involving these and 20 other “controversial, high profile, or sensitive” topics will get extra scrutiny under Health Secretary Robert F. Kennedy Jr.

ProPublicaNational Cancer Institute Employees Can’t Publish Information on These Topics Without Special Approval
More from ProPublica
#RFKJR#CENSORSHIP#CANCER
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